Kev tshuaj xyuas raws li waveform ntawm kev co taub hau siv cov cim tsis muaj kev taug qab algorithm nrog 2D-video

Jung, zoo siab uas koj rov qab los koom nrog podcast hnub no. Koj tau los ua ib tus neeg tuaj koom tas li. Thiab Dr. Bj, nws yog ib qho koob hmoov uas koj tau tuaj koom hnub no. Yog li kuv thawj lo lus nug rau nej ob leeg thiab ib leeg ntawm nej tuaj yeem koom nrog qhov no, kuv xav nug nej tias nej tau xav li cas txog kev ua qhov kev tshawb fawb no?

Qhov no puas yog ib yam dab tsi uas koj tau xav txog ib ntus, los yog koj puas tau ntsib cov thev naus laus zis tshiab, cov algorithm uas siv video, thiab xav tias qhov no yuav siv tau zoo? Los yog koj puas tau txais kev tshoov siab los ntawm kev ntsib tus neeg mob tshwj xeeb?

Dr. Beomseok Jeon: Qhov teeb meem no pib thaum kuv koom nrog Dystonia Tremor Working Group, uas tau teeb tsa los ntawm MDS uas yog los ua haujlwm tshwj xeeb rau qhov teeb meem dystonic tremor no.

Pawg neeg ua haujlwm no yog Hyder Jinnah ua tus thawj coj thiab muaj [00:02:00] ntau tus kws tshaj lij xws li Alberto Albanese, Alfonso Fasano, Sanjay Pandey, Rick Helmich, Marie Vidailhet, Marina Tjissen, Aasef Shaikh, Roger Elble, thiab Victor Fung. Thiab ib tug ntawm cov tswv cuab yog Mark Hallett, uas tau tas sim neej ob peb lub lis piam dhau los, uas tau pab txhawb nqa txoj haujlwm no los ntawm kev sau ntau cov lus pom zoo thiab xa cov yeeb yaj kiab rau cov neeg mob rau peb.

Peb xav ua tsaug rau nws heev.

Dr. Mitra Afshari: Muaj tseeb tiag. Kuv xav tias peb txhua tus nco Dr. Hallett thiab peb tab tom xav txog nws. Yog li nws zoo li muaj ntau txoj haujlwm uas tau mus rau hauv lub tswv yim tom qab qhov project no thiab ntau txoj haujlwm sawv cev rau ntau lub zog thaum nws los txog rau dystonia, ua ib feem ntawm pawg neeg ua haujlwm dystonia. Thiab yog li ntawd hauv kev tshawb fawb no, koj lub hom phiaj yog nrhiav txoj hauv kev zoo dua rau [00:03:00] kev tshuaj xyuas kev co thiab dystonia caj dab thiab cov neeg mob uas muaj kev co taub hau. Anecdotally, kuv xav tias peb txhua tus tau nyob hauv qhov chaw uas peb tau nug peb lub peev xwm los sib txawv qhov kev co taub hau dystonic los ntawm kev co taub hau uas pom hauv kev co tseem ceeb. Peb paub, kev co dystonic zoo li tsis muaj rhythmic. Lawv zoo li tsis muaj sinusoidal, lawv ntau dua jerky. Lawv tsis yog hom kev co ntshiab, tiag tiag uas peb xav txog, thiab thaum koj kuj tab tom nrhiav cov lus qhia ntxiv zoo li hauv qab tonic posturing, muaj qee kis uas tuaj yeem nyuaj heev. Yog li koj nug cov lus nug yooj yim, cia peb coj qhov peb xav tias peb paub txog lub suab thiab qhov sinusoidality ntawm cov kev co taub hau no thiab cia peb muab lawv tso rau hauv kev sim. Yog li koj siv cov txheej txheem pom kev hauv computer yooj yim los tshuaj xyuas cov yeeb yaj kiab 2D ntawm cov neeg mob uas muaj kev co taub hau, tshwj xeeb [00:04:00] taug qab kev txav mus los ntawm qhov ntswg, thiab koj tau saib cov neeg mob yav tom ntej thiab rov qab los ntawm cov yeeb yaj kiab khaws cia.

Raws li koj tau hais, Dr. Bj, koj tau koom tes nrog Dystonia Coalition Group uas paub zoo uas Buzz Jinnah coj ntawm Emory University hauv Atlanta hauv Tebchaws Meskas thiab koj tau siv lawv cov ntaub ntawv khaws cia ntawm cov neeg mob dystonia ntawm cov yeeb yaj kiab ntawd. Tus neeg mob tshwj xeeb nrog lub taub hau tshee hnyo thiab koj kuj tau sau npe cov neeg mob ntawm koj lub tsev kawm ntawv thiab txawm tias tau siv qee cov yeeb yaj kiab ntawm cov neeg mob ET uas tau kuaj MRI tsom mus rau ultrasound, yog tias kuv hais yog lawm, rau lawv cov tes tshee hnyo. Koj kuj tuaj yeem lees paub koj cov kev tshawb pom los ntawm cov kev tshuaj xyuas waveform video tsis muaj cim no. Koj tau lees paub tias cov kev tshawb pom no tau pom zoo nrog kev ntsuas lub cev sensor los ntawm kev sib txuas cov ntaub ntawv nrog lub gyroscope uas tau muab tso rau ntawm tus neeg mob lub taub hau. Yog li Dr. [00:05:00] BJ lossis Dr. Shin, koj puas tuaj yeem piav qhia luv luv txog koj cov txheej txheem hauv kev tshawb fawb no, thiab thaum kawg, koj tau ua dab tsi? Koj puas tuaj yeem pleev xim rau hauv peb tus mloog lub siab ntawm txhua yam no ua haujlwm li cas? 

Dr. Jung Hwan Shin: Yog. Ua tsaug ntau ntau rau koj cov lus nug. Zoo siab tau ntsib koj sai sai no, Mitra. Kuv tau txaus siab rau kev tshuaj xyuas video ntawm kev txav mus los hauv kev mob txav mus los suav nrog tus kab mob Parkinson thiab qhov tseeb kuv qhov kev tshawb fawb tsom mus rau qhov kev tshuaj xyuas video no ntawm bradykinesia, postures thiab gait tshwj xeeb, Kuv tsom mus rau kev ua qhov kev tshuaj xyuas gait nrog cov yeeb yaj kiab ob seem. Tab sis nws yog qhov nthuav heev uas kuv tau txaus siab rau qhov kev tshuaj xyuas video no, uas txhua yam pib los ntawm kuv lub sijhawm PhD uas kuv tau ua qhov kev tshawb fawb yooj yim siv cov qauv nas. Rov qab rau hnub thaum kuv ua PhD, kuv muaj teeb meem nrhiav tus nas hnav zoo li endoscopes.

Yog li muaj cov kab zoo li [00:06:00] txuas rau lub taub hau nas thiab txoj kev ib txwm ua rau cov kab txuas rau lub taub hau nas tsis meej pem, zoo li endoscopy nrog tus Tsov tus tw ntawm nas. Yog li peb yuav tsum los nrog txoj kev sib txawv los tshuaj xyuas qhov kev mus los ntawm nas. Thiab peb pom tias cov txheej txheem pom kev hauv computer tuaj yeem ua rau taug qab nas yam tsis muaj cov cim txuas rau nas tiag tiag. Yog li, kuv qhov kev kawm PhD, kuv siv ntau cov algorithms los taug qab qhov chaw ntawm nas. Thiab tom qab kuv rov qab los rau lub tsev kho mob, kuv pom tias peb muaj ntau cov yeeb yaj kiab. Peb muaj ntau cov yeeb yaj kiab ntawm kev co, kev taug kev, bradykinesia, yog li vim li cas ho tsis siv cov algorithm no rau cov neeg mob? Yog li ntawd yog txhua yam nws pib.

Yog li kuv tau ua ntau txoj kev tshawb fawb txawm tias ntawm ntau yam phenomenology ntawm tus neeg mob nrog kev saib xyuas ntawm tus xibfwb Bj. Thiab qhov project no pib [00:07:00] los ntawm cov rooj sib tham hauv chav kuaj uas BJ tau qhia cov kev sib tham txog dystonia tremor pawg uas nws tau hais. Txawm hais tias muaj kev txhais meej ntawm tremor thiab dystonia, tab sis thaum nws los txog rau qhov tseeb phenomenology ntawm cov neeg mob yuav muaj ntau qhov kev tsis pom zoo vim tias seb peb puas pom rhythmicity thiab sinusoidal yog qhov subjective heev. Yog li, Bj tau hais tias vim li cas ho tsis ntsuas cov sinusoidal thiab rhythmicity nrog cov video-based algorithm vim nws qhia txog dab tsi vim nws yog kev tshuaj xyuas video. Okay. Yog li nws tau hais tias nws yuav muaj txiaj ntsig zoo heev. Yog li qhov project no pib nrog txoj kev xav uas tsav los ntawm kev xav, tsis yog txoj kev tsav los ntawm cov ntaub ntawv. Yog li nws tau meej heev los ntsuas sinusoidality thiab rhythmicity, tsis yog tag nrho cov yam ntxwv ntawm qhov tremor no. Yog li kuv xav tias qhov ntawd tau meej heev thiab ua rau txoj kev uas ua rau kev tshawb fawb [00:08:00] ua tau zoo dua thiab ua haujlwm tau zoo hauv qee txoj kev. Yog li ntawd, peb tsuas ntsuas qhov ntswg ntawm qhov tshee taub hau xwb vim tias yog peb yuav tsum tshuaj xyuas ntau yam ntxwv ntawm qhov tshee taub hau, peb yuav tsum siv txoj kev peb seem vim tias qhov tshee taub hau mus rau hauv txoj kev peb seem. Tab sis peb lub hom phiaj yog ntsuas rhythmicity thiab sinusoidality. Yog li peb tsis tas yuav ntsuas tag nrho cov yam ntxwv ntawd, tab sis peb yuav tsum tau txais cov waveform ntawm tus neeg mob.

Tsuas yog taug qab lub qhov ntswg ntawm lub taub hau tshee hnyo peb tuaj yeem tshuaj xyuas seb lawv cov tremor waveforms zoo li cas lossis sinusoidal. Thiab peb yuav tsum tsim peb tus kheej cov kev ntsuas los ntsuas qhov rhythmicity thiab sinusoidality, uas zoo li kev sim thiab qhov yuam kev. Thiab peb tau los nrog cov kev ntsuas zoo tshaj plaws uas tuaj yeem [00:09:00] qhia txog qhov rhythmicity thiab sinusoidality, uas ntau tus kws tshaj lij tremor thiab dystonia pom zoo cov neeg sau ntawv ntawm peb cov ntawv. Txoj kev tshawb fawb no peb xav kom paub tseeb tias qhov rhythmicity thiab sinusoidality parameters uas peb xam yog qhov tseeb. Yog li peb tau lees paub nrog peb cov cohorts sab hauv siv lub gyroscope. Peb pom tias cov kev ntsuas ntawd sib phim thiab txij thaum pib, peb siv zoo li qhov zaus siab, tsis muaj cov yeeb yaj kiab siab, 240 thav duab ib ob cov yeeb yaj kiab vim peb xav kom paub tseeb tias peb tsis tuaj yeem muaj qhov cuam tshuam zoo li qhov kev tshuaj xyuas vim peb paub cov yeeb yaj kiab kaw tus neeg mob nrog kev tshee hnyo nrog tus nqi qis. Tom qab ntawd koj qhov kev tshuaj xyuas yuam kev rau qhov sib txawv ntawm qhov kev tshee hnyo tiag tiag. Yog li peb siv 240 thav duab ib ob cov yeeb yaj kiab, tab sis peb [00:10:00] thaum kawg pom tias txawm tias muaj 30 thav duab ib ob thaum peb down sample cov yeeb yaj kiab, nws tseem qhia tau tias muaj kev pom zoo zoo nrog lub gyroscope. Yog li, peb xav sim cov algorithm no rau ntau cov yeeb yaj kiab, tsis yog los ntawm peb lub chaw, tab sis cov yeeb yaj kiab los ntawm thoob plaws ntiaj teb. Thiab Dystonia Coalition tau muab kev txhawb nqa ntau ntawm kev sib koom cov yeeb yaj kiab ntawd. Tsis yog tsuas yog cov neeg mob dystonia cervical xwb, tab sis kuj yog cov neeg mob tremor tseem ceeb. Thiab qhov ntawd yog li cas peb tau qhia txog kev faib tawm ntawm rhythmicity thiab sinusoidality hauv cov neeg mob dystonia cervical thiab cov neeg mob tremor tseem ceeb. Yog li qhov tshwm sim, qhov tshwm sim tseem ceeb ntawm txoj kev tshawb fawb no yog tias peb tau qhia txog kev faib tawm ntawm cov neeg mob dystonia cervical tseem ceeb hauv kev rhythmicity thiab sinusoidality, uas tau ntsuas los ntawm kev tshuaj xyuas video.

Dr. Mitra Afshari: Tau kawg. Yog li koj coj qee yam uas koj tau [00:11:00] tau siv rau koj cov qauv tsiaj thiab koj yeej siv rau tib neeg.

Thiab koj muaj peev xwm sim ib qho kev xav yooj yim, thiab tau lees paub qhov kev xav ntawd tiag tiag. Yog li nws yeej yog ib txoj hauv kev muaj tswv yim. Thiab yog li koj tau nkag mus rau qee qhov txiaj ntsig ntawm daim ntawv. Yog li kuv xav tias txhua tus neeg xav paub, puas yog dystonic tremors hauv cervical dystonia, puas yog lawv tsis tshua muaj rhythmic thiab tsawg dua sinusoidal? Thiab nws puas zoo li koj cov txiaj ntsig haum nrog qhov kev xav ntawd?

Dr. Beomseok Jeon: Tau kawg, yog. Kev txav taub hau hauv cervical dystonia yog qhov phem dua, tsis tshua muaj rhythmic thiab tsawg dua sinusoidal hauv ntau qhov xwm txheej. Yog vim li cas qee tus neeg hauv peb pawg tsis xav siv lo lus dystonic tremors vim tias tremors yuav tsum yog rhythmic thiab sinusoidal. Qee tus neeg hauv peb pawg tsis pom zoo nrog lo lus dystonic tremors hauv cervical [00:12:00] dystonia, tab sis muaj qee tus neeg uas muaj kev txav mus los hauv cervical dystonia, uas muaj cervical dystonia, uas yog rhythmic thiab zoo nkauj sinusoidal. Nws xaiv nyob rau hauv qhov ntau ntawm qhov tseem ceeb tremor uas yog qhov pib ntawm qhov teeb meem, uas yuav tsum tau daws yav tom ntej.

Dr. Mitra Afshari: Zoo kawg li. Thiab koj puas pom tias qhov tremor amplitude tau cuam tshuam rau koj cov txiaj ntsig? Kuv xav tias qhov ntawd yog ib qho ntawm cov variables uas koj tau saib tshwj xeeb. Koj puas tuaj yeem tshuaj xyuas cov kev tshawb pom ntawd nrog peb?

Dr. Jung Hwan Shin: Yog, muaj tseeb tiag. Nws muaj feem cuam tshuam nrog qhov amplitude thiab peb muaj ntau cov yeeb yaj kiab uas peb tau tshuaj xyuas thiab peb pom tias muaj cov neeg mob uas muaj qhov amplitude loj. Muaj cov neeg mob uas muaj qhov amplitude me thiab peb pom tias cov sinusoidality thiab rhythmicity index ntawd muaj feem cuam tshuam nrog qhov tremor amplitude.

[00:13:00] Yog tias qhov av qeeg loj heev, lawv feem ntau yog rhythmic thiab sinusoidal. Tab sis nyob rau hauv pawg qis dua, lawv feem ntau yog sinusoidal tsawg dua thiab rhythmic tsawg dua. Tab sis qhov txwv ntawm peb txoj kev tshawb fawb yog tias peb tsis tuaj yeem ntsuas qhov loj ntawm qhov av qeeg vim peb siv cov yeeb yaj kiab ob sab.

Yog li qhov deb ntawm lub taub hau thiab lub koob yees duab sib txawv ntawm cov tib neeg. Yog tias peb tuaj yeem tswj qhov deb, tej zaum peb tuaj yeem txiav txim siab qhov amplitude. Tab sis hauv kev tshawb fawb no peb ua tsis tau li ntawd. Yog li peb tau qhia tsis ncaj qha tias qhov tremor amplitude cuam tshuam nrog lub rhythmicity thiab sinusoidality index raws li tetra scale thiab qhov ambiguous tremor amplitude los ntawm tus neeg mob. Tab sis qhov no tau kawm hauv kev tshawb fawb yav dhau los, suav nrog ntau tus kws tshawb fawb suav nrog Dr. Aasef qhia tias qhov tseeb [00:14:00] tremor muaj feem cuam tshuam nrog lawv cov sinusoidality thiab rhythmicity ntawm tremors.

Dr. Mitra Afshari: Yog li txawm hais tias muaj qee qhov kev txwv txog li cas koj tau txais cov ntaub ntawv ntawd, qhov koj pom zoo li haum rau cov kev tshawb fawb yav dhau los txog qhov loj ntawm kev co. Yog li muaj qee yam nyob ntawd. Ib qho kev tshawb pom nthuav yog tias nyob rau hauv pawg neeg rau cov neeg mob ET, thaum muaj kev sib hloov siab dua hauv sinusoidality uas yog, ntau dua qhia tias nws yog qhov tseem ceeb tremor. Muaj qhov tseeb tsawg dua ntawm qhov kev kuaj mob raws li video thiab qhov kev kuaj mob tiag tiag. Yog li ntawd qhov tseeb ntawm kev kuaj mob yog li 64% thaum nws los txog rau ET piv rau li 82% thaum nws los txog rau lub taub hau dystonia cervical. Koj xav li cas txog qhov kev tshawb pom no?

Dr. Beomseok Jeon: Dua li ntawm qhov dystonia ntawm lub caj dab muaj qhov tsis tshua muaj zog, tsis tshua muaj lub taub hau sinusoidal [00:15:00] kev txav uas pom tseeb heev uas sib txawv ntawm dystonia ntawm lub caj dab los ntawm lwm yam kev co. Tab sis qee tus neeg mob uas muaj dystonia muaj qhov kev txav uas muaj zog, sinusoidal, uas zoo ib yam li qhov kev co tseem ceeb. Yog vim li cas tsuas yog raws li qhov rhythmicity thiab sinusoidality, lawv tsis tuaj yeem sib txawv ntawm ET piv rau cervical dystonia.

Qhov ntawd yog qhov teeb meem. Qhov ntawd yog qhov teeb meem uas seb cov neeg mob uas muaj mob cervical dystonia puas tuaj yeem muaj kev txav mus los ntawm lub taub hau rhythmic, sinusoidal uas tuaj yeem hu ua tremors.

Dr. Mitra Afshari: Muaj tseeb tiag. Thiab qhov ntawd yog qhov kev sib tw uas coj peb rov qab mus rau vim li cas cov kev tshawb nrhiav no thiaj li ua tiav. Yog li muab tag nrho cov no ua ke, koj xav tias cov lus coj mus tsev los ntawm qhov kev tshawb nrhiav no yog dab tsi? Zoo li ET thiab lub taub hau dystonia cervical [00:16:00] tremors yeej yog txhua yam ntawm spectrum, puas yog? Koj yuav sau cov lus coj mus tsev los ntawm koj txoj kev kawm hnub no li cas?

Dr. Jung Hwan Shin: Zoo. Yog li ntawd, raws li Xibfwb BJ tau hais, peb pom muaj kev sib txawv ntawm qhov sib txawv ntawm lub caj dab dystonia nrog kev tshee hnyo thiab tseem nyob hauv tus neeg mob tseem ceeb tshee hnyo. Kuv xav tias txoj kev tshawb fawb no muab qhov ntawd hauv lub ntiaj teb tiag tiag uas kev kho mob tuaj yeem ntsuas tau zoo li tus neeg mob thiab nws nyuaj heev rau kev pom zoo txawm tias cov kws tshaj lij. Yog li muaj daim ntawv nthuav heev los ntawm Elan Louis uas siv cov yeeb yaj kiab ntawm tsib tus neeg mob thiab lawv tau nug xya tus kws tshaj lij MDS los kuaj mob yog qhov kev tshee hnyo tseem ceeb lossis dystonic jerky dystonia. Thiab [00:17:00] tag nrho cov kws tshaj lij tau kuaj mob cov neeg mob hauv ntau yam kev tshwm sim. Ib txhia kws tshaj lij hais tias tag nrho cov neeg mob yog jerky dystonia thiab qee tus kws tshaj lij hais tias lawv txhua tus yog cov neeg mob tseem ceeb tshee hnyo. Thiab lwm tus kws tshaj lij nyob nruab nrab. Yog li peb tuaj yeem pom hauv lub ntiaj teb tiag tiag nws yuav nyuaj heev.

Txawm tias peb muaj lub ntsiab lus ntawm txhua qhov phenomenology yuav nyuaj heev. Yog li kuv xav tias hauv cov lus ntawd siv cov kev ntsuas lub hom phiaj tuaj yeem muab cov lus qhia, cov lus qhia los daws qhov kev sib tham thiab kev tsis sib haum xeeb no. Yog li kuv xav tias nws yuav nyuaj heev rau kev dhia mus rau hauv qee qhov phenomenology raws li tsuas yog siv rhythmicity thiab sinusoidality. Peb tuaj yeem muaj qhov kev ntsuas lub hom phiaj, tab sis nrog qhov no peb tuaj yeem siv lwm cov lus qhia hauv kev kho mob zoo li kev ua kom pom tseeb lossis cov postures ua ke peb tuaj yeem ua rau ntau dua [00:18:00] pom zoo rau kev piav qhia zoo dua ntawm phenomenology. Rau kuv, kuv xav tias yog siv cov thev naus laus zis digital tshiab tshaj plaws nrog kev piav qhia ntawm cov tsos mob tuaj yeem pab tau ntau txoj hauv kev. Peb tuaj yeem muaj kev faib tawm zoo li pom hauv peb cov lus qhia. Thiab peb tuaj yeem pib sib tham los ntawm qhov ntawd. Yog li ntawd yog qhov peb xav tawm tswv yim rau thaj chaw hauv qhov kev co no. Ib qho ntawm cov khoom uas peb tau ua, tshiab hauv kev tshawb fawb no uas peb tau txais sinusoidality Index. Cov ntsuas kev sib hloov tau raug kawm thiab muaj ntau yam kev ntsuas uas tau tsim kho ntau xyoo, tab sis cov ntsuas sinusoidality tau raug tshaj tawm tshiab hauv kev tshawb fawb no. Thiab qhov laj thawj uas peb tuaj yeem ua nws yog tias peb siv kev tshuaj xyuas raws li video. Peb tuaj yeem muaj cov nthwv dej ntawm qhov av qeeg. Thiab qhov ntawd yog [00:19:00] vim li cas peb thiaj li tuaj yeem tau txais cov ntsuas sinusoidality, uas sawv cev rau ob lub ntsiab lus tseem ceeb ntawm kev co. Nws yuav tsum yog rhythmic thiab sinusoidal thiab siv cov thev naus laus zis digital tshiab tsim, kuv xav tias cov txheej txheem ntawd tuaj yeem siv rau ntau lwm yam phenomenology thiab cov khoom tsis sib haum xeeb hauv kev txav mus los tsis zoo.

Dr. Mitra Afshari: Muaj tseeb tiag. Kuv xav tias koj paub cov kev tshuaj xyuas 2D video no, thaum lawv yooj yim heev, lawv yeej yog ib qho cuab yeej muaj zog heev los ntxiv rau koj lub thawv cuab yeej thaum koj ua kev kuaj mob thiab thaum kawg peb tuaj yeem ua qhov kev kuaj mob raug tshaj plaws thiab tsim cov kev kho mob zoo dua thiab muaj txiaj ntsig zoo. Hauv qhov kev tshawb nrhiav no, koj tsuas yog saib ntawm qhov kawg ntawm lub qhov ntswg. Tab sis koj tau hais txog qhov no ua ntej tias saib rau yav tom ntej, koj tuaj yeem tau txais lwm yam kev ntsuas txawm tias los ntawm cov yeeb yaj kiab 2D. Qhov ntawd puas yog? Lwm yam kev txav mus los lossis [00:20:00] axes uas koj. Qhov ntawd tuaj yeem muab cov ntaub ntawv ntxiv los qiv rau kev kuaj mob. Qhov no puas yog ib yam dab tsi uas koj pawg neeg tab tom ua haujlwm tam sim no lossis xav txog kev tshawb nrhiav yav tom ntej nrog pawg kawm dystonia.

Dr. Jung Hwan Shin: Muaj tseeb tiag. Raws li peb tau hais lawm, peb tsuas yog tsom mus rau qhov kawg ntawm lub qhov ntswg xwb. Lub laj thawj tseem ceeb yog peb xav pom qhov sinusoidality thiab rhythmicity ntawm, lub taub hau tshee hnyo. Muaj ntau lwm cov qauv nrog kev tshuaj xyuas video uas tuaj yeem ua qauv rau peb qhov ntev ntawm lub taub hau thiab siv nws los ntsuas zoo li lub kaum sab xis ntawm lub taub hau qaij, lub taub hau tig. Yog li ntawd. Yog li muaj ntau txoj hauv kev los tshuaj xyuas qhov dystonic tremors hauv lub taub hau lossis txawm tias hauv tes. Yog li peb xav txav qhov project no mus tom ntej, siv cov txheej txheem no thiab vam tias yuav tsim cov algorithm zoo dua thiab zoo dua yav tom ntej [00:21:00] hauv kev piav qhia txog cov phenomenology nyuaj.

Dr. Mitra Afshari: Ua tsaug ntau ntau rau Dr. Shin, Dr. BJ. Qhov no yeej yog ib qho kev sib tham zoo heev hnub no. Peb xav ua tsaug rau koj pab neeg tag nrho rau kev ua haujlwm ntawm qhov project no, tag nrho pawg kawm dystonia rau txhua txoj haujlwm uas koj tau ua, thiab peb xav ua tsaug rau koj rau kev siv sijhawm tawm ntawm koj cov sijhawm tsis khoom los tham nrog peb. Kuv paub tseeb tias nws tsis yooj yim rau kev qhia cov txheej txheem ntawm kev tshawb fawb no hauv lub rooj sib tham no, tab sis nej ob leeg tau ua haujlwm zoo heev. Yog li xav ua tsaug rau koj thiab txog rau lub sijhawm tom ntej, bye-bye.

Dr. Beomseok Jeon: Bye.

Dr. Jung Hwan Shin: Ua tsaug. [00:22:00] [00:23:00]